目的 调查淮河沿岸肝吸虫病流行的危险因素。方法 采用实验流行病调查法,对中间宿主、终宿主和沿岸部分居民作现场查询、体检和粪检。结果 现场捕获的豆螺、沼螺体内可分离出有尾鞘的单尾蚴,用尾蚴感染淡水鱼可获囊蚴,用囊蚴感染家猫获肝吸虫成虫;从淮河沿岸部分居民及其放养的家猪粪便中可检出肝吸虫卵。结论 淮河沿岸存在多种肝吸虫病流行的危险因素。 Objective To investigate the risk factors for the prevalence of hepatic flukes along the Huaihe River. Methods The experimental epidemiological investigation method was used to make inquires, physical examinations and excrement tests on the intermediate host, the final host and some residents along the coast. Results One-cercaria larvae were isolated from the snails and marsupials captured in the field, the larvae were infected with the cercariae, the larvae were infected with the metacercariae and the adult cats were infected with the larvae. Liver pig eggs can be detected in feces. Conclusions There are many risk factors for the prevalence of clonorchiasis along the Huaihe River.