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目的:探讨薄芝糖肽注射液联合前列地尔治疗糖尿病足的临床疗效。方法:选择2011年3月~2012年2月收治的糖尿病足患者32例,分为观察组和对照组,每组16例,对照组采用常规治疗方法加前列地尔,观察组此基础上联合薄芝糖肽注射液进行治疗。比较两组临床症状积分改善情况及临床疗效。结果:两组治疗后发凉怕冷、疼痛麻木、间歇性跛行及溃疡坏疽症状积分与治疗前相比差异均有统计学意义(P<0.05),观察组改善情况明显优于对照组(P<0.05)。观察组总有效率为87.5%,对照组总有效率为75%,两组总有效率差异有统计学意义(P<0.05)。结论:采用薄芝糖肽注射液联合前列地尔治疗糖尿病足临床疗效明确,值得临床推广。
Objective: To investigate the clinical efficacy of baozhi glycopeptide injection combined with alprostadil in the treatment of diabetic foot. Methods: Thirty-two diabetic foot patients who were treated from March 2011 to February 2012 were divided into observation group and control group, with 16 cases in each group. The control group was treated with conventional treatment plus alprostadil, and the observation group was united Bozhi glycopeptide injection for treatment. The improvement of clinical symptom scores and clinical efficacy were compared between the two groups. Results: After treatment, the two groups were cold and cold, pain numbness, intermittent claudication and ulcer gangrene symptom scores compared with before treatment were significantly different (P <0.05), the observation group improved significantly better than the control group (P <0.05). The total effective rate was 87.5% in the observation group and 75% in the control group. The total effective rate in the two groups was statistically significant (P <0.05). Conclusion: The treatment of diabetic foot with capsaicin injection combined with alprostadil has a definite clinical effect and is worthy of clinical promotion.