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观测了14例儿童单用速尿产生抗药性水肿22次时联合应用甲苯喹唑磺胺(甲喹胺)(0.2～0.4mg/kg/天(与速尿2～4mg/kg/天)对排钠利尿的作用。单用速尿与联合用药对比:尿量从24±14ml/kg/天增至51ml/kg/天(P<0.01);钠排出量从34±5mEq/天增至155±176mEq/天(P<0.01)。2例严重低白蛋白血症(血清白蛋白水平低于1.5g/dL)但肾功能正常和5例慢性肾功
A total of 14 cases of children with furosemide drug-resistant edema alone were observed 22 times combined with toluolazosulfan (methotrizine) (0.2 ~ 0.4mg / kg / day (with furosemide 2 ~ 4mg / kg / day) The effect of sodium diuretic versus furosemide alone and in combination: urinary output increased from 24 ± 14 ml / kg / day to 51 ml / kg / day (P <0.01); sodium excretion increased from 34 ± 5 mEq / day to 155 ± 176mEq / day (P <0.01) .2 patients with severe hypoalbuminemia (serum albumin level less than 1.5g / dL) but normal renal function and 5 patients with chronic renal failure