脐血干细胞是一类具有多向分化潜能的原始祖细胞,具备自我更新和增殖的能力,在特定条件诱导下可以分化为不同细胞,逐渐作为临床组织工程的来源细胞。近年来随着对脐血干细胞的不断研究,发现其在创面修复中具有明显的优势,成为创面临床治疗的一条新途径。本文从脐血干细胞的生物学特性、采集与冻存、体外扩增等方面对创面修复的研究进行综述。 Umbilical cord blood stem cells are a kind of primitive progenitor cells with multidirectional differentiation potential, possess the ability of self-renewal and proliferation, can differentiate into different cells under the specific conditions and gradually become the source cells of clinical tissue engineering. In recent years, with the umbilical cord blood stem cells continue to study and found that wound repair has obvious advantages, as a new way of clinical treatment of wounds. This review summarizes the research on wound healing in terms of the biological characteristics of cord blood stem cells, collection and cryopreservation, and in vitro amplification.