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恢复和维持窦性心律是房颤(AF)治疗的重要策略。默克公司开发的维纳卡兰对急性AF转复的疗效优于其他药物,有可能成为替代胺碘酮的有效药物。本文综述维纳卡兰药动学特点、作用机制、疗效及安全性。
Recovery and maintenance of sinus rhythm is an important strategy for the treatment of atrial fibrillation (AF). Merck’s development of Waina Ka Lan on the efficacy of acute AF is superior to other drugs, may become an effective alternative to amiodarone drugs. This review summarizes the pharmacokinetic characteristics, mechanism of action, efficacy and safety of Vina Karan.