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目的:结合病理组织学探讨联合应用彩色超声成像和核磁共振(MRI)对乳腺癌的诊断价值。方法:回顾性分析经手术或组织学活检病理证实的74例乳腺癌患者(97个病灶)及良性肿块70例患者(75个病灶)的术前彩色超声成像及核磁共振检查资料,比较两种检查方法及联合应用的诊断效率,同时与病理组织学结果对照。结果:超声、核磁共振及两者联合应用,对乳腺癌诊断的敏感性分别为76.3%、82.5%和87.6%,特异性分别为92.0%、88.0%和96.0%,符合率分别为83.1%、84.9%和91.3%,统计学分析比较无显著性差异(P>0.05)。两种检查方法及联合应用的经济性分析显示,采用超声检查,其费用支出仅为MRI的约1/10,为联合应用法的约1/11;如都实施穿刺病理检查,则超声穿刺法的费用支出较MRI或联合法节约一半以上。结论:超声、核磁共振检查对乳腺癌的诊断都具有较高的特异性和敏感性,而联合检查可以有效地提高符合率。考虑到经济性效率,采用超声结合病理穿刺诊断乳腺癌更适于高危人群筛查。
Objective: To investigate the diagnostic value of combined application of color ultrasound imaging and magnetic resonance imaging (MRI) in breast cancer with histopathology. Methods: Preoperative color ultrasound imaging and MRI data of 74 breast cancer patients (97 lesions) and 70 benign tumors (75 lesions) confirmed by surgery or histological biopsy were retrospectively analyzed. Check the diagnostic methods and the combined application of efficiency, and histopathological results with the control. Results: The sensitivity of ultrasound, MRI and the combination of them was 76.3%, 82.5% and 87.6% respectively, the specificity was 92.0%, 88.0% and 96.0% respectively, the coincidence rates were 83.1% 84.9% and 91.3% respectively. There was no significant difference in statistical analysis (P> 0.05). The economic analysis of the two test methods and the combined application shows that the cost of the ultrasound examination is only about 1/10 of that of MRI and about 1/11 of that of the combined application method. For example, both the puncture pathological examination and the ultrasound puncture method Expenditure on expenses more than halved compared with MRI or joint law. Conclusion: Ultrasonography and magnetic resonance imaging have high specificity and sensitivity in the diagnosis of breast cancer, and combined examination can effectively improve the coincidence rate. Taking into account the economic efficiency, the use of ultrasound combined with pathological diagnosis of breast cancer screening is more suitable for high-risk groups.