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2例高血压病患者使用硝苯地平致牙龈增生。例1,43岁男性患者口服硝苯地平10 mg,2次/d。用药5年后患者出现牙龈乳头增大伴有龈缘充血。停用硝苯地平,改为坎地沙坦酯。1个月后症状好转。例2,78岁女性患者因血压控制不佳给予硝苯地平30 mg,1次/d。用药1年后患者出现牙龈乳头增大伴有轻度充血。停用硝苯地平,改为氨氯地平。2周后症状缓解。
Two cases of nifedipine induced gingival hyperplasia in hypertensive patients. Cases of male patients aged 1,43 nifedipine 10 mg, 2 times / d. 5 years after treatment, patients with gingival papilla increases with gingival congestion. Disable nifedipine, to candesartan cilexetil. After 1 month, the symptoms improved. Example 2 A 78-year-old female patient was given nifedipine 30 mg once daily for poor blood pressure control. 1 year after treatment, patients with gingival papilla increases with mild congestion. Disable nifedipine, to change amlodipine. Symptoms were relieved after 2 weeks.