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目的 观察糖尿病不同病程大鼠视网膜上核因子 κB(NF κB)的活性变化与血小板源生长因子 B(PDGF B)的表达情况 ,以及与糖尿病视网膜病变 (DR)的关系 ,探讨它们在DR发病机制中的作用。 方法 将SD大鼠 6 0只随机分为糖尿病组、对照组 (各 30只 )。糖尿病组采用链脲佐菌素(ST
Objective To observe the changes of nuclear factor κB (NF κB) activity, the expression of platelet-derived growth factor B (PDGF B) and the relationship with diabetic retinopathy (DR) in different stages of diabetic rats and to explore their roles in the pathogenesis of DR In the role. Methods Sixty SD rats were randomly divided into diabetic group and control group (30 rats each). Diabetes group using streptozotocin (ST