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目的观察老年女性乳腺癌根治术中应用氟-芬合剂与氯胺酮全凭静脉麻醉的临床效果及安全性,为后期应用提供参考。方法选取我院收治的80例老年女性乳腺癌患者为研究对象,患者均行乳腺癌根治手术及全凭静脉麻醉,按照麻醉药物不同将患者分为实验组与对照组各40例,对照组行七氟醚静吸复合麻醉,实验组予氟-芬合剂及氯胺酮行全凭静脉麻醉,观察两组患者麻醉前后的一般情况。结果实验组麻醉前至停氧后的血氧饱和度比较,差异有显著性(P<0.01);组间在术后拔管时间、呼吸恢复时间、苏醒时间、苏醒期(疼痛、躁动、导管不耐受)及满意度比较,差异均有统计学意义(均P<0.05)。结论老年女性乳腺癌患者行根治手术时给予氯胺酮及氟-芬合剂进行全凭静脉麻醉的效果显著,患者生命体征平稳,安全性高,值得临床推广应用。
Objective To observe the clinical effect and safety of Fluoro-Fupi Mixture and ketamine combined with intravenous anesthesia in radical mastectomy of elderly women and provide reference for the later application. Methods 80 cases of elderly women with breast cancer treated in our hospital were selected as study subjects. All patients underwent radical operation and full-vein anesthesia for breast cancer. According to different anesthetic drugs, the patients were divided into experimental group and control group (n = 40) Sevoflurane inhalation anesthesia, the experimental group to fluoride - Fung mixture and ketamine line of total intravenous anesthesia, the two groups were observed before and after general anesthesia. Results There was significant difference (P <0.01) between the oxygen saturation before anesthesia and after stopping oxygen in the experimental group. There was no significant difference between the two groups in the time of extubation, respiration recovery time, recovery time, recovery period (pain, restlessness, Intolerance) and satisfaction, the differences were statistically significant (P <0.05). Conclusion Elderly female patients with breast cancer undergoing radical surgery to give ketamine and fluorine - Fen mixture of the total intravenous anesthesia effect is significant, patients with stable vital signs, high safety, worthy of clinical application.