自从Hillestad于1957年发表急性早幼粒细胞性白血病(以下简称APL)并指出本病具有①病情急剧、病程短促,②末稍血及骨髓内所看到的白细胞以早幼粒细胞占优势,③出血倾向明显,④血沉不亢进等四个特点以来,引起人们的重视,以后陆续有所报导。Bernard等于1959年用本病名报告20例,Gingold等由于早幼粒细 Since Hillestad published acute promyelocytic leukemia in 1957 (hereinafter referred to as APL) and pointed out that the disease has ① rapid disease, short course of disease, ② the end of the blood and bone marrow seen in leukocytes preponderant promyelocytic, ③ obvious bleeding tendency, ④ euco-hygrosis and other four features, aroused people’s attention, one after another have been reported. Bernard is equal to 1959 reports of 20 cases with this disease name, Gingold et al