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环加氧酶2(COX-2)抑制药是新一代的非甾体类抗炎药,不但有更好的消炎镇痛效果,而且能减轻胃肠道药物不良反应。本文分析了COX-2抑制药在治疗心血管系统疾病应用中发生的不良事件,并评估这类药物的药效经济学,为抗炎药物的选择提供指导依据。
Cyclooxygenase 2 (COX-2) inhibitor is a new generation of non-steroidal anti-inflammatory drugs, not only better anti-inflammatory analgesic effect, but also reduce gastrointestinal adverse drug reactions. In this paper, we analyzed the adverse events of COX-2 inhibitors in the treatment of cardiovascular diseases and evaluated the pharmacodynamics of these drugs to provide guidance for the selection of anti-inflammatory drugs.