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目的:探讨硬膜外连续泵注芬太尼和布比卡因应用于产妇分娩的镇痛效果以及对产妇及新生儿的影响。方法:选择孕产妇228例为镇痛组,设同期相同条件的产妇180例为对照组,镇痛组产妇给予布比卡因125 mg和芬太尼0.2 mg经硬膜外泵注至胎儿顺利娩出停药。比较两组镇痛效果及分娩结局。结果:硬膜外连续泵注对产妇生命体征、血氧饱和度无明显影响,镇痛效果好;镇痛组第一产程时间明显短于对照组,第二产程、产后出血量及新生儿Apgar评分两组比较无统计学差异,镇痛组产妇剖宫产率明显低于对照组。结论:硬膜外连续泵注布比卡因和芬太尼是较安全理想的无痛分娩方法,镇痛效果确切,可缩短产程,降低剖宫产率,对母婴无不良影响。
Objective: To investigate the analgesic effect of epidural continuous infusion of fentanyl and bupivacaine in maternal labor and its effects on maternal and newborn infants. Methods: Two hundred and eighty-eight pregnant women were selected as the analgesic group. 180 maternal women under the same conditions were selected as the control group. The women in the analgesic group were injected with 125 mg bupivacaine and 0.2 mg fentanyl via the epidural pump to the fetus Delivery stopped. The analgesic effect and delivery outcome were compared between the two groups. Results: Epidural continuous injection had no significant effect on the vital signs and blood oxygen saturation of maternal women, and had a good analgesic effect. The time of first stage of labor in analgesic group was significantly shorter than that in control group, second stage of labor, postpartum hemorrhage and neonatal Apgar Scores were no significant difference between the two groups, analgesic cesarean section rate was significantly lower than the control group. Conclusion: Epidural continuous infusion of bupivacaine and fentanyl is a safe and ideal method for painless delivery. The analgesic effect is exact. It can shorten the labor process, reduce the rate of cesarean section and have no adverse effect on the mother and the infant.