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为评估脂蛋白(a)[LP(a)]、载脂蛋白(APO)异常与脑卒中的相关性及危险度,对脑卒中组及对照组共380例进行LP(a)、APOA1、APOB100测定。结果显示,以上指标异常同脑卒中有相关性,而与疾病对照无相关性;RR是健康及疾病对照的数倍至10余倍,其中LP(a)、APOA1异常对脑卒中发病尤为重要,且是相对特异的因素。LP(a)、APO异常是脑卒中发病的危险因素,LP(a)、APOA1是筛查高危人群并进而指导防治的较好指标。
To assess the association and risk of abnormalities of apolipoproteins (a) [LP (a)], apolipoproteins (APO) with stroke, 380 patients in the stroke and control groups underwent LP (a), APOA1, APOB100 Determination. The results showed that the above indexes were abnormally related to stroke and no correlation with disease control. RR was several times to 10 times of health and disease control. Among them, abnormalities of LP (a) and APOA1 were particularly important for stroke, And is a relatively specific factor. LP (a), APO abnormalities are the risk factors of stroke, LP (a), APOA1 is a good indicator of screening high-risk groups, and thus guide the prevention and treatment.