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目的挖掘大骨节病临床证候的病位、病性证素,探寻大骨节病的证素组合规律,提高大骨节病临床辨证水平。方法对957例大骨节病患者中医四诊信息进行采集,经过中医专家组经验辨证,规范证候名称,然后进行证素提取,建立相应数据库,用SPSS17.0统计软件包进行频次和频率的统计描述,对大骨节病证素分布规律进行探讨。结果临床调查确定病位证素4个:肾、肝、脾、经络;病性证素12个:湿、寒、阳虚、风、血虚、血瘀、精亏、气虚、热、痰、阴虚、气滞。结论证素分布规律揭示了大骨节病证候特点是虚、邪、瘀,虚为肝脾肾亏虚,邪为风寒湿邪,瘀为痰瘀胶结。
Objective To explore the clinical symptoms of Kashin-Beck disease disease location, disease syndrome factors, to explore the rules of Kashin-Beck disease syndrome combination to improve Kashin-Beck disease clinical syndrome level. Methods A total of 957 patients with Kashin-Beck disease were enrolled in the four diagnostic tests of TCM information. After the syndrome differentiation of TCM expert group, the name of the syndrome was standardized, and the syndromes were extracted. The corresponding database was established. The frequency and frequency of the data were calculated with SPSS17.0 statistical package Description, the distribution of bone mass disease factors discussed. Results The clinical investigation confirmed 4 kinds of disease-bitch syndromes: kidney, liver, spleen and meridian; 12 syndromes of pathogenic factors: wet, cold, yang, wind, blood deficiency, blood stasis, Yin, Qi stagnation. Conclusion The distribution of syndrome elements reveals that the symptoms of Kashin-Beck disease are vacuity, evil, stasis, deficiency of liver, spleen and kidney, deficiency of wind, dampness and dampness as well as stasis of phlegm and blood stasis.