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目的:针对甲状腺功能减退性心脏病展开临床用药研究,了解小剂量磷酸肌酸钠联合甲状腺素治疗优越性。方法:选取我院近年收治的此类患者共70例,随机分为对照组及观察组。对照组仅使用甲状腺素治疗,观察组在此基础上另加入小剂量磷酸肌酸钠治疗。对比两组患者CK、CK-MB、LDH、HR、SV、LVEF以及LVDd这几项指标变化情况。结果:两组患者在HR方面均无明显变化,对照组仅在CK、CK-MB这三方面明显改善,而治疗后这三个方面组件对比明显,观察组改善程度更深。结论:小剂量磷酸肌酸钠联合甲状腺素治疗甲状腺功能减退性心脏病在短期治疗效果上能够达到较好的程度,帮助改善患者心脏功能状态,适合临床推广使用。
Objective: To investigate the clinical use of hypothyroidism and thyroxine in the treatment of hypothyroidism. Methods: A total of 70 cases of these patients admitted to our hospital in recent years were randomly divided into control group and observation group. The control group only treated with thyroxine, the observation group was additionally treated with low-dose sodium creatine phosphate. The changes of CK, CK-MB, LDH, HR, SV, LVEF and LVDd in two groups were compared. Results: There was no significant change in HR between the two groups. The control group only improved obviously in three aspects of CK and CK-MB. After treatment, the comparison of three components was obvious and the observation group improved more deeply. Conclusion: Small doses of sodium creatine phosphate combined with thyroxine in the treatment of hypothyroidism can achieve a better therapeutic effect in short-term, which can help improve the cardiac function of patients and is suitable for clinical use.