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拉氧头孢系氧头孢烯类抗生素,为第三代头孢类抗生素(海南省海灵制药厂和日本盐野义制株式会社合作生产)。它具有血药浓度高,半衰期长,对革兰阴性菌、革兰阳性菌作用强,对β-内酰胺酶稳定等特点。我科于1994年4月至1997年12月,用拉氧头孢治疗老年重症下呼吸道感染64例,现将结果报道如下。 1资料与方法 1.1一般资料 根据老年人下呼吸道感染判断标准筛选住院患者64例,男性48例,女性16例;年龄61～86岁,平均71.2岁。其中慢性支气管炎急性发作43例,重症支气管哮喘伴感染8例,支气管扩张症并感染8例,肺脓疡5例。除5例无基础疾病外,59例均伴有慢支炎、阻塞性肺气肿、支气管哮喘或肺心病等慢性呼吸系疾病史,病史多在20年以上。临床症状以咳嗽、咯痰及发热为主。
Deoxy cephalosporin oxygen cephalosporins antibiotics for the third generation of cephalosporins antibiotics (Hainan Province, Hai Ling Pharmaceutical Co., Ltd. and Japan Yoshihito Yasuhito co-production). It has high plasma concentration, long half-life, strong effect on Gram-negative bacteria, Gram-positive bacteria, β-lactamase stability and so on. My department in April 1994 to December 1997, with deoxythiazide in the treatment of elderly patients with severe lower respiratory tract infection in 64 cases, the results reported below. 1 Materials and Methods 1.1 General Information According to the criteria for the elderly to determine the lower respiratory tract screening 64 cases of inpatients, 48 males and 16 females; aged 61 to 86 years, mean 71.2 years. Including chronic bronchitis in 43 cases of acute attack, severe bronchial asthma with infection in 8 cases, bronchiectasis and infection in 8 cases, 5 cases of lung abscess. Except for 5 cases without underlying diseases, all 59 cases had chronic respiratory diseases such as chronic myositis, obstructive pulmonary emphysema, bronchial asthma or pulmonary heart disease, with a history of more than 20 years. Clinical symptoms to cough, expectoration and fever-based.