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目的 观察女性急性心肌梗塞 (AMI)患者接受静脉溶栓治疗的临床效果。方法 回顾分析 3年内接受静脉溶栓 3 0 2例 (AMI)患者中的 83例女性AMI的临床疗效。结果 ( 1 ) 83例女性AMI与 2 1 9例男性患者比较 ,溶栓后梗塞相关血管 (IRA)再通率明显为低 ( 57 8%比 73 5% ,P <0 0 1 ) ,尤其3 8例≥ 60岁的老年女性比 92例老年男性明显为低 ( 55 9%比 73 0 % ,P <0 0 2 5)。 ( 2 )经溶栓治疗的男性AMI患者比女性的 5周死亡率 ( 4 1 %比 1 4 5% ,P <0 0 1 )及中度以上心衰率 ( 1 4 2 %比 2 6 5% ,P<0 0 5)明显为低。结论 国人女性AMI患者接受溶栓治疗安全有效 ,但其临床疗效似乎低于男性患者。
Objective To observe the clinical effect of intravenous thrombolysis in female patients with acute myocardial infarction (AMI). Methods The clinical efficacy of 83 AMI women receiving intravenous thrombolysis in 302 patients (AMI) within 3 years was retrospectively analyzed. Results (1) Compared with 219 male patients, the AMI of 83 female patients was significantly lower (57 8% vs 73 5%, P 0 01) after thrombolysis, especially for 3 Eight elderly women ≥ 60 years of age were significantly lower than 92 elderly men (55 9% vs. 73 0%, P 0 025). (2) The 5-week mortality rate (41 1% vs 145.5%, P 0 01) and the moderate-to-severe heart failure rate (142% vs 25 65% %, P <0 0 5) was significantly lower. Conclusions Chinese women with AMI are safe and effective in thrombolytic therapy, but their clinical efficacy seems to be lower than that of male patients.