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母婴传播是病毒性乙型肝炎的重要传播途径。80年代应用乙肝血源疫苗阻断母婴传播取得了较理想的效果，但要从人血中提取抗原，价格昂贵，且有潜在的安全问题。目前，新一代乙型肝炎表面抗原基因工程疫苗（简称乙肝基因疫苗）已研制成功，其安全性和免疫原性已被证实。1990～199
Mother-to-child transmission is an important route of transmission of viral hepatitis B. In the 1980s, the application of Hepatitis B blood-borne vaccine to block mother-to-child transmission achieved better results, but the extraction of antigens from human blood was expensive and posed potential safety issues. Currently, a new generation of hepatitis B surface antigen genetic engineering vaccine (hepatitis B gene vaccine for short) has been successfully developed, its safety and immunogenicity has been confirmed. 1990 ~ 199