Peptide aptamers:The versatile role of specific protein function inhibitors in plant biotechnology

来源 :Journal of Integrative Plant Biology | 被引量 : 0次 | 上传用户:a443532159
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
In recent years,peptide aptamers have emerged as novel molecular tools that have attracted the attention of researchers in various fields of basic and applied science,ranging from medicine to analytical chemistry.These artificial short peptides are able to specifically bind,track,and inhibit a given target molecule with high affinity,even molecules with poor immunogenicity or high toxicity,and represent a remarkable alternative to antibodies in many different applications.Their use is on the rise,driven mainly by the medical and pharmaceutical sector.Here we discuss the enormous potential of peptide aptamers in both basic and applied aspects of plant biotechnology and food safety.The different peptide aptamer selection methods available both in vivo and in vitro are introduced,and the most important possible applications in plant biotechnology are illustrated.In particular,we discuss the generation of broadbased virus resistance in crops, “reverse genetics” and aptasensors in bioassays for detecting contaminations in food and feed.Furthermore,we suggest an alternative to the transfer of peptide aptamers into plant cells via genetic transformation,based on the use of cell-penetrating peptides that overcome the limits imposed by both crop transformation and Genetically Modified Organism commercialization. In recent years, peptide aptamers have emerged as novel molecular tools that have attracted the attention of researchers in various fields of basic and applied science, ranging from medicine to analytical chemistry. The artificial short peptides are able to specifically bind, track, and inhibit a given target molecule with high affinity, even molecules with poor immunogenicity or high toxicity, and represent a remarkable alternative immunities in many different applications. their use is on on the rise, driven mainly by the medical and pharmaceutical sector. He we discuss the enormous potential of peptide aptamers in both basic and applied aspects of plant biotechnology and food safety. The different peptide aptamer selection methods available both in vivo and in vitro are introduced, and the most important possible applications in plant biotechnology are illustrated. generation of broadbased virus resistance in crops, “reverse genetics ” and aptasensors in bioassa ys for illustrative contaminations in food and feed. Future co., we suggest an alternative to the transfer of peptide aptamers into plant cells via genetic transformation, based on the use of cell-penetrating peptides that overcome the limits imposed by both crop transformation and Genetically Modified Organism commercialization.
其他文献
哈萨克斯坦国家信息化与通信局局长阿斯卡尔·朱马加利耶夫2006年7月27日在政府会议上说,哈萨克斯坦将降低因特网的上网费。他说:“2006年9月1日起上网费将下调25%,2007年和200
要想成为一名彩铃制作者,那你就要考虑以下几点:第一,现在有越来越多的人使用彩铃,它的最大受众群是年轻人。第二,如今最流行的彩铃,莫过于好的流行歌曲类、好的原创搞笑类以
北京的一位读者来信问:目前社会各界都非常关注青少年的教育问题,作为青少年生活居住地的社区更应该充分发挥自己的优势,把关心教育青少年作为社区工作的一项内容,但是对社
你可能认识一些开朗的人,也可能认识一些害羞的人。心理学家对不同类型的人给予了不同的划分。他们把开朗的人称之为“外向者”;把喜欢安静和愿意与少数几个人相处的人称之为
在煤田地区,特别是在零星开采的小煤窑地区,浅基础井口地基很常见。由于年代已久,一些老井口在地面上很难发现,只有当基槽开挖到一定深度后才能看到,而这时常因已定点的建筑
儿子上四年级期中考试成绩不理想,语文90分,数学87分,在班里排名倒数第二,不光孩子受批评,就连我这个家长也被“请”到学校,被班主任老师狠狠数落了一 My son did not scor
本文通过对4万亿投资效果进行分析,特别对其中民营企业发展问题进行探究,并借此提出相关的建议和意见。 This article analyzes the effect of 4 trillion investment, espe
发生在今年年初的清华大学学生用硫酸喂食北京动物园的熊,导致熊严重烧伤的事件给教育者提出了人材的 “综合素质”问题。同样,我们也 在深思一个更具体的 问题—— Tsinghu
根据自考教育的实践,提出“开放教育”和自考教育的再开放,是我国加入WTO对教育战略地位的新认识。一、自考教育在我国的开放和实践,为开放奠定了基础自学考试是对自学者进
<正> 《明史》卷74《职官志》三曰:“洪武元年命在京兵马指挥司并管市司,每三日一次校勘街市斛斗、秤尺,稽考牙僧姓名,时其物价。”(中华局标点本第1815页)按:“牙僧”误,应作“牙儈”。“儈”字和