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目的对云南战区腹泻病原菌进行监测,掌握其腹泻病原谱的构成和流行病学特征,为军队和地方腹泻病的防控及诊治提供重要依据。方法采集监测点肠道门诊腹泻患者新鲜粪便标本,按统一制定的监测方案,操作规程检测志贺菌、沙门菌、致泻性大肠埃希菌(EIEC、ETEC、EPEC、EHEC、EAggEC)、小肠结肠炎耶尔森菌、空肠弯曲菌、霍乱弧菌、副溶血弧菌、气单胞菌、类志贺邻单胞菌以及其它肠道病原菌。结果从588例腹泻患者粪便标本中检出各类病原菌220株,检出率为37.41%。其中肺炎克雷伯菌居首位(6.80%)、费劳地枸橼酸菌次之(5.95%)、居第三位的是志贺菌(4.25%)、列第四位的是奇异变形菌和阴沟肠杆菌(3.23%)、排第五至第七位的分别是产酸克雷伯菌(2.89%)、侵袭性大肠杆菌(2.21%)和气单胞菌(1.53%)。不同年龄组检出率为29.11%～48.34%之间,其中36～45岁年龄组检出率最高,男女性别间差异无统计学意义(P>0.05)。病原检出率5、8、9月份较高。结论通过对腹泻病原菌监测,了解腹泻病原菌的组成,建立病原谱,掌握其流行病学特征,为军队和地方腹泻病的研究、防控、流行病学调查等提供重要参考资料。
Objective To monitor the pathogenic bacteria of diarrhea in the theater of war in Yunnan Province and master the constitution and epidemiological characteristics of the diarrhea pathogenic spectrum and provide an important basis for prevention and control of diarrhea in the military and local areas. Methods Fresh stool samples from patients with diarrhea in the gut clinic at the monitoring point were collected and monitored according to a unified monitoring program and operating procedures to detect Shigella, Salmonella and diarrheal Escherichia coli (EIEC, ETEC, EPEC, EHEC and EAggEC) Yersinia enterocolitica, Campylobacter jejuni, Vibrio cholerae, Vibrio parahaemolyticus, Aeromonas, Pichia pastoris, and other enteric pathogens. Results A total of 220 pathogenic bacteria were detected in stool specimens of 588 diarrhea patients, the detection rate was 37.41%. Among them, Klebsiella pneumoniae ranked the first (6.80%), followed by Ficus citric acid (5.95%), the third was Shigella (4.25%), the fourth was singular deformation Enterobacter cloacae (3.23%), and Klebsiella oxytoca (2.89%), Escherichia coli (2.21%) and Aeromonas spp. (1.53%) were the fifth to the seventh place. The detection rate was 29.11% ~ 48.34% in different age groups, of which 36-45 years old group had the highest detection rate with no significant difference between male and female (P> 0.05). Pathogen detection rate of 5, 8, September higher. Conclusion By monitoring the pathogens of diarrhea, understanding the composition of pathogenic bacteria in diarrhea, establishing the pathogen spectrum, mastering the epidemiological characteristics and providing important references for the research, prevention and control, epidemiological investigation of army and local diarrhea.