通过复习国内文献,对488例晚发性维生素K缺乏症进行了综合分析。结果发现,年龄在15d～2月者占89.6%,男女之比为2.96∶1,母乳喂养者占89.7%。全部病例均有不同部位的出血倾向,其中颅内出血的发生率达92.7%。病死率为20.2%。出血部位和诊治迟早是影响本病预后的关键因素。维生素K可有效预防本病,建议全部婴儿出生后均应注射维生素K。 By reviewing the domestic literature, we conducted a comprehensive analysis of 488 cases of late onset vitamin K deficiency. The results showed that age 15d ~ February accounted for 89.6%, the ratio of male to female was 2.96: 1, breastfeeding accounted for 89.7%. All cases had different parts of the bleeding tendency, of which the incidence of intracranial hemorrhage reached 92.7%. The case fatality rate was 20.2%. The bleeding site and diagnosis and treatment sooner or later affect the prognosis of this disease a key factor. Vitamin K can effectively prevent the disease, it is recommended that all infants should be injected vitamin K after birth.