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目的:探讨盐酸纳美芬在治疗急性乙醇中毒中的应用。方法:回顾性分析我院急诊科2009-06-2011-12300例中重度乙醇中毒患者的临床资料,将300例患者随机分为治疗组和对照组,每组各150例。治疗组在常规治疗基础上给予盐酸纳美芬治疗;对照组在常规治疗基础上给予纳诺酮治疗。观察2组患者清醒时间及症状消失时间。结果:治疗组用药30min后病情明显好转,并稳定。与对照组相比,治疗组的症状缓解时间明显优于对照组。结论:在常规治疗的基础上联合应用盐酸纳美芬对抢救早期急性乙醇中毒,疗效显著。
Objective: To investigate the application of nalmefene hydrochloride in the treatment of acute alcoholism. Methods: A retrospective analysis of our hospital emergency department 2009-06-2011-12300 cases of moderate to severe alcoholism in patients with clinical data, 300 patients were randomly divided into treatment group and control group, 150 cases in each group. The treatment group was treated with nalmefene hydrochloride on the basis of routine treatment; the control group was treated with norgetonone on the basis of conventional treatment. Two groups of patients were observed awake time and symptoms disappear time. Results: The treatment group 30min after the disease was significantly improved, and stable. Compared with the control group, the treatment group was significantly better than the control group. Conclusion: The combination of nalmefene hydrochloride on the basis of conventional treatment of early acute alcohol poisoning, a significant effect.