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自Magnius及Espmark(1971)在HBsAg阳性血清中发现e抗原(eAg)抗体(eAb)系统后,为乙型肝炎的研究增加了新的途径。eAg只能在HBsAg阳性患者的血清中才可以找到,目前对其性质虽尚未弄清楚,但已知其抗原性与HBsAg有别。一般认为eAg的存在是反映乙型肝炎病毒存在及增殖的重要指标,并认为与肝功能损害,肝组织学异常及预后相关,但近年也有认为这种相关不是绝对的(上海医学4:13,1978)。为此,我院对在1977年6月间同时用琼脂扩散法及对流电泳法检定为eAg
The discovery of the e antigen (eAg) antibody (eAb) system in HBsAg-positive sera by Magnius and Espmark (1971) added a new approach to the study of Hepatitis B. eAg can only be found in the serum of patients with HBsAg-positive, although its nature is not yet clear, but its antigenicity is known to be different from HBsAg. It is generally believed that the presence of eAg is an important indicator of the presence and proliferation of hepatitis B virus and is believed to be associated with impaired liver function, abnormal liver histology and prognosis, but in recent years it has also been suggested that this association is not absolute (Shanghai Medical 4:13, 1978). To this end, our hospital pairs in June 1977 at the same time by agar diffusion and convective electrophoresis assay eAg