论文部分内容阅读
Objective This paper proposes a nonparametric procedure of the sample size determination for survival rate test. Methods Using the classical asymptotic normal procedure yields the required homogenetic effective sample size and using the inverse operation with the prespecified value of the survival function of censoring times yields the required sample size. Results It is matched with the rate test for censored data, does not involve survival distributions, and reduces to its classical counterpart when there is no censoring. The observed power of the test coincides with the prescribed power under usual clinical conditions. Conclusion It can be used for planning survival studies of chronic diseases.
Objective This paper proposes a nonparametric procedure of the sample size determination for survival rate test. The Using as the classical asymptotic normal procedure yields the required homogenetic effective sample size and using the inverse operation with the prespecified value of the survival function of censoring times yield the required Results It is matched with the rate test for censored data, does not involve survival distributions, and reduces to its classical counterpart when there is no censoring. The observed power of the test coincides with the prescribed power under usual clinical conditions. It can be used for planning survival studies of chronic diseases.