集落刺激因子(CSA)是醣蛋白。粒细胞及巨噬细胞集落的形成需要有CSA,其主要来源是成熟的巨噬细胞及单核细胞。锂可以使小鼠及人中性粒细胞增多,产生或释放CSA增多。作者们研究了在制备鼠肺条件培养液时加入氯化锂对产生的CSA质和量的影响,发现在加入3mM的氯化锂于40mg鼠肺和1ml的无血清的MEM Alpha Medium培养48小时所得到的条件培养液中CSA的 Colony stimulating factor (CSA) is a glycoprotein. The formation of granulocyte and macrophage colony requires CSA, the main source of which is mature macrophages and monocytes. Lithium can make mice and human neutrophils increase, produce or release increased CSA. The authors studied the effect of addition of lithium chloride on the quality and quantity of CSA produced during the preparation of murine lung conditioned medium and found that incubation with 3 mM lithium chloride in 40 mg murine lung and 1 ml of serum-free MEM Alpha Medium for 48 hours The resulting conditioned medium was CSA