论文部分内容阅读
目的 评价DF方案化疗和放疗综合治疗局部晚期食管癌的疗效。方法 DF方案 (DDP + 5 -Fu)化疗和放疗综合治疗 98例 ,单纯放射治疗 92例。结果 化放组和单放组 1、2、3年生存率分别为 60 2 %、43 9%、3 1 6%和 44 6%、2 9 3 %、16 3 % ,3年局控率分别为 45 9%和 3 1 5 % ,3年远处转移率分别为 11 2 %和 2 2 8% ,化放组明显优于单放组 (P <0 0 5 )。化放组无严重的毒副反应。结论 DF方案化疗和放疗综合治疗能提高局部晚期食管癌的局控率 ,减少远处转移和提高生存率 ,且不增加严重的毒副反应
Objective To evaluate the efficacy of DF chemotherapy combined with radiotherapy in the treatment of locally advanced esophageal cancer. Methods DF regimen (DDP + 5 -Fu) combined chemotherapy and radiotherapy was used in 98 patients and radiotherapy alone in 92 patients. Results The 1-, 2-, and 3-year survival rates of chemotherapy group and radiotherapy group were 60 2%, 43 9%, 31 6% and 44 6%, 293%, and 16 3%, respectively. For 45 9% and 3 1 5%, the 3-year distant metastasis rates were 11 2% and 2 8%, respectively. The chemoradiotherapy group was significantly better than the radiotherapy group (P <0 05). There are no serious toxic and side reactions in the chemical release group. Conclusion DF regimen combined with chemotherapy and radiotherapy can improve the local control rate of local advanced esophageal cancer, reduce distant metastasis and improve survival rate without increasing serious side effects.