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本文综述了近年来关于胆色素代谢的若干新发现: 一、在血红蛋白的降解过程中,首先形成的中间产物为高铁血红素的假说已利用标志高铁血红素的实验加以证实,但关于高铁血红素的进一步降解,则旧日由高铁血红素分出三价铁而形成原卟啉1 × a的理论不能为同位素实验所证实。原卟啉与抗坏血酸的偶联氧化作用并不能形成胆色素,须高铁血红素,高铁血红白蛋白,血红蛋白及高铁血红蛋白等化合物与抗坏血酸的偶联氧化始可形成胆色素,因此设想
This review summarizes several new discoveries about bile pigment metabolism in recent years: First, the hypothesis that the first intermediate product is hemin during the degradation of hemoglobin has been confirmed by the experiment of using hemin marker. However, Of the further degradation, then the old separation of ferric hematin and the formation of protoporphyrin 1 × a theory can not be confirmed by isotope experiments. Protoporphyrin and ascorbic acid coupling oxidation can not form a porphyra pigment, hematin, methemoglobin, hemoglobin and methemoglobin and other compounds coupled with ascorbic acid oxidized to form the pigment, so imagine