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目的探讨强直性脊柱炎的早期临床特征,为其早期初步诊断提供依据。方法对51例确诊为强直性脊柱炎早期患者的临床症状和体征按性别分别进行统计学分析。结果本组资料中有52%男性有休息痛和晨僵,女性为53.84%和46.15%;活动后疼痛缓解男女分别为80%和96.15%。骶髂关节检查的阳性率为80%,指地距离大于10 cm者,男女分别为64%和42%,Schober试验阳性者男女分别为20%和3.84%;胸廓活动度小于5 cm者,男性8%,女性3.84%。血沉和C反应蛋白的阳性率分别为21.57%和47.06%。结论晨僵和休息后疼痛加重以及活动后缓解是强直性脊柱炎早期重要的临床症状。骶髂关节检查和指地距离具有较高的阳性率。血沉和C反应蛋白有辅助诊断意义。
Objective To investigate the early clinical features of ankylosing spondylitis and provide the basis for its early diagnosis. Methods The clinical symptoms and signs of 51 patients with early diagnosis of ankylosing spondylitis were analyzed by sex respectively. Results 52% of the men in this group had rest pain and morning stiffness, 53.84% and 46.15% of women, and 80% and 96.15% of men and women were relieved after the activity. The positive rate of sacroiliac joint examination was 80%, referring to the distance greater than 10 cm were 64% and 42% for men and women, Schober test positive for men and women were 20% and 3.84%, respectively; chest activity less than 5 cm, male 8%, women 3.84%. The positive rates of ESR and C-reactive protein were 21.57% and 47.06% respectively. Conclusions Morning stiffness and post-rest pain and post-exercise remission are important early clinical symptoms of ankylosing spondylitis. Sacroiliac joint examination and refer to the distance has a high positive rate. Erythrocyte sedimentation rate and C-reactive protein have diagnostic significance.