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目的探讨分析沙美特罗联合替卡松粉治疗咳嗽变异型哮喘(CVA)的有效性及安全性。方法选取在我科进行治疗的243例CVA患者,随机分为观察组和对照组,观察组122例,给予沙美特罗替卡松粉吸入剂治疗;对照组121例,应用布地奈德吸入剂治疗;4周为1疗程,治疗8~12周。观察两组患者治疗后症状的改善情况及药物的不良反应。结果经治疗后对照组总有效率84.3%,观察组总有效率为94.3%,两组比较差异有统计学意义(P<0.05);两组咳嗽症状积分均较治疗前显著下降(P<0.01),但观察组比对照组下降更为明显(P<0.05)。结论沙美特罗替卡松粉吸入剂对CVA具有良好的治疗效果及较好的安全性。
Objective To investigate the efficacy and safety of salmeterol combined with ticasone powder in the treatment of cough variant asthma (CVA). Methods A total of 243 patients with CVA who were treated in our department were randomly divided into observation group and control group. 122 cases in the observation group were treated with salmeterol and fluticasone powder inhalation. In the control group, 121 cases were treated with budesonide inhalation Treatment; 4 weeks for a course of treatment, treatment of 8 to 12 weeks. Observed two groups of patients after treatment to improve the symptoms and adverse drug reactions. Results After treatment, the total effective rate of the control group was 84.3%, the total effective rate of the observation group was 94.3%, the difference between the two groups was statistically significant (P <0.05); the cough symptom scores of both groups were significantly lower than those before treatment (P <0.01 ), But the observation group decreased more significantly than the control group (P <0.05). Conclusion Salmeterol truss powder inhalation on CVA has good therapeutic effect and good safety.