Intra-body communication (IBC) is a new, emerging, short-range and human body based communication methodology. It is a technique to network various devices on human body, by utilizing the conducting properties of human tissues, suitable for currently fast developing Body area network (BAN)/Body sensor network (BSN). IBC is believed to have advantages in power consumption, electromagnetic radiation, interference from external electromagnetic noise, security, and restriction in spectrum resource.In this article, the authors develop two models, which are analytical and empirical approaches, for comparing the performance and accuracy of IBC on a human limb. Through in vivo experiment of five volunteers,both models basically match with the experimental result with equivalent circuit model superior than electromagnetic model in term of maximum error.