新生儿病理性黄疸114例病因分析

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目的分析新生儿病理性黄疸的病因。方法对内蒙古包头医学院第一附属医院2005-01-2009-12收治的114例新生儿病理性黄疸进行回顾性分析。结果 114例新生儿病理性黄疸中围产因素42例(36.84%),母乳性黄疸38例(33.33%),感染因素26例(22.81%),溶血因素3例(2.63%),其他5例(4.39%)。新生儿病理性黄疸病因以围产因素、母乳性黄疸为主,其次为感染、新生儿溶血病等,围产因素包括新生儿窒息7例,早产8例,胎膜早破1例,宫内窘迫2例,羊水粪染5例,高龄初产3例,剖宫产14例,产妇妊高症2例,感染因素为新生儿败血症6例,新生儿肺炎10例,巨细胞病毒感染4例,皮肤感染3例,脐炎3例。ABO母子血型不合溶血病3例,其他:先天性胆道闭锁1例,咽下综合征1例,新生儿硬肿症2例,胎粪性便秘1例等。结论新生儿病理性黄疸以围生期因素、母乳性黄疸、感染因素为主,故为了降低新生儿病理性黄疸的发病率,应加强围产期保健工作,提高产科质量,加强新生儿护理密切观察黄疸出现的时间和程度,积极防治新生儿感染,可以降低新生儿病理性黄疸的发生。 Objective To analyze the etiology of neonatal pathological jaundice. Methods A retrospective analysis of 114 neonatal pathological jaundice admitted to the First Affiliated Hospital of Baotou Medical College from January 2005 to December 2009 was performed. Results Among the 114 cases of neonatal pathological jaundice, 42 cases (36.84%) were infants, 38 cases (33.33%) had breast milk jaundice, 26 cases were infected (22.81%), 3 cases were hemolysis (2.63%) and 5 cases (4.39%). The causes of neonatal pathological jaundice were mainly perinatal factors and breast milk jaundice, followed by infection and neonatal hemolytic disease. Perinatal factors included neonatal asphyxia in 7 cases, premature birth in 8 cases, premature rupture of membranes in 1 case, intrauterine 2 cases of distress, 5 cases of meconium amniotic fluid, 3 cases of advanced age, cesarean section in 14 cases, 2 cases of maternal pregnancy-induced hypertension, neonatal infection in 6 cases, neonatal pneumonia in 10 cases, cytomegalovirus infection in 4 cases , Skin infections in 3 cases, 3 cases of omphalitis. ABO mother and child blood group incompatible hemolytic disease in 3 cases, the other: congenital biliary atresia in 1 case, swallowing syndrome in 1 case, neonatal scleroderma in 2 cases, meconium-like constipation in 1 case. Conclusion neonatal pathological jaundice with perinatal factors, breast milk jaundice, infection-based, so in order to reduce the incidence of neonatal pathological jaundice, we should strengthen perinatal care, improve the quality of obstetrics and strengthen the nursing of newborns close Observe the time and extent of jaundice, and actively prevent neonatal infection, can reduce the incidence of neonatal pathological jaundice.
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