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目的:探讨玻璃体切割联合白内障手术治疗增殖性糖尿病视网膜病变的疗效。方法:选择2013年1月至2016年6月我院接诊的90例增殖性糖尿病视网膜病变患者,通过随机数表法分为观察组(n=45)和对照组(n=45)。对照组使用玻璃体切割术+晶状体切除术,观察组使用玻璃体切割术+超声乳化吸除术。比较两组最佳矫正视力、泪液白介素(IL)-2、角膜荧光素染色(FL)、泪膜破裂时间(BUT)以及泪液分泌试验(SIt)的结果以及并发症的发生情况。结果:手术后,观察组最佳矫正视力明显优于对照组(P<0.05),泪液IL-2水平明显高于对照组(P<0.05),FL显著低于对照组,BUT、SIt明显高于对照组(P<0.05),囊膜浑浊、虹膜新生血管、角膜水肿、干眼症的发生率均显著低于对照组(P<0.05)。结论:玻璃体切割联合超声乳化吸除术治疗增殖性糖尿病视网膜病变患者的效果显著,可促进术后视力恢复,改善泪液分泌,并减少并发症。
Objective: To investigate the efficacy of vitrectomy combined with cataract surgery in the treatment of proliferative diabetic retinopathy. Methods: Ninety patients with proliferative diabetic retinopathy admitted to our hospital from January 2013 to June 2016 were divided into observation group (n = 45) and control group (n = 45) by random number table. In the control group, vitrectomy and lensectomy were used. In the observation group, vitrectomy and phacoemulsification were used. The results of best corrected visual acuity, interleukin (IL) -2, corneal fluorescein staining (FL), tear film break-up time (BUT) and tear secretion test (SIt) were compared between the two groups and the incidence of complications. Results: After operation, the best corrected visual acuity of the observation group was significantly better than that of the control group (P <0.05), IL-2 level of tear was significantly higher than that of the control group (P <0.05), FL was significantly lower than that of the control group In the control group (P <0.05), the incidence of cyst turbidity, iris neovascularization, corneal edema and dry eye were significantly lower than those in the control group (P <0.05). Conclusion: Vitrectomy combined with phacoemulsification in patients with proliferative diabetic retinopathy has significant effect, which can promote postoperative visual acuity recovery, improve tear secretion and reduce complications.