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The title compounds 3-(3,5-bis(trifluoromethyl)phenyl)quinoline(1) and 3-(4-fluoro-3-methylphenyl)quinoline(2) were synthesized through Suzuki-Miyaura Cross coupling reaction of 3-bromoquinoloine with aryl boronic acids.The title compounds were characterized by single-crystal X-ray diffraction,1H NMR,13C NMR,EI-MS,elemental analysis and IR.The crystals of 3-(3,5-bis(trifluoromethyl)phenyl)quinoline(C17H9F6N,Mr = 341.25) belongs to the monoclinic system,space group P21n,a = 12.3072(13),b = 4.9378(6),c = 24.493(2) ,V = 1473.1(3) 3,Z = 4,Dc = 1.539 Mg m-3,λ = 0.71073 ,μ = 0.144 mm-1,F(000) = 688,the final R = 0.0715 and wR = 0.1873 for 1875 observed reflections with I > 2σ(I) and the crystal of 3-(4-fluoro-3-methylphenyl)quinoline(C16H12FN,Mr = 237.27) belongs to the orthorhombic system,space group Pca21,a = 23.794(2),b = 3.9094(3),c = 25.669(2) ,V = 2387.7(4) 3,Z = 8,Dc = 1.320 Mg m-3,λ = 0.71073 ,μ = 0.088 mm-1,F(000) = 992,the final R = 0.0534 and wR = 0.1188 for 2270 observed reflections with I > 2σ(I).
The title compounds 3- (4-fluoro-3-methylphenyl) quinoline (2) were synthesized through Suzuki-Miyaura Cross coupling reaction of 3-bromoquinoloine with aryl boronic acids. The title compounds were characterized by single-crystal X-ray diffraction, 1H NMR, 13C NMR, EI-MS, elemental analysis and IR.The crystals of 3- (3,5-bis (C17H9F6N, Mr = 341.25) belongs to the monoclinic system, space group P21n, a = 12.3072 (13), b = 4.9378 (6), c = 24.493 (2) 4, Dc = 1.539 Mg m -3, λ = 0.71073 , μ = 0.144 mm -1, F (000) = 688, the final R = 0.0715 and wR = 0.1873 for 1875 observed reflections with I> 2σ (I) and The crystal of 3- (4-fluoro-3-methylphenyl) quinoline (C16H12FN, Mr = 237.27) belongs to the orthorhombic system, space group Pca21, a = 23.794 (2), b = 3.9094 (3), c = 25.669 2 = 87, V = 2387.7 (4) 3, Z = 8, Dc = 1.320 Mg m-3, λ = 0.71073 , μ = 0.088 mm-1, F wR = 0.1188 for 2270 observed reflections with I> 2σ (I).