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目的观察匹伐他汀治疗糖尿病高胆固醇血症的疗效。方法 100例糖尿病高胆固醇血症患者,随机分为对照组和观察组,每组50例。两组患者均给予常规的降糖治疗,在此基础上,对照组给予阿托伐他汀治疗,观察组给予匹伐他汀治疗。观察两组患者的空腹血糖、高密度脂蛋白胆固醇(HDL-C)及不良反应发生率。结果观察组患者的空腹血糖、HDL-C及不良反应发生率明显优于对照组,差异均具有统计学意义(P<0.05)。结论匹伐他汀治疗糖尿病高胆固醇血症的疗效显著,可以有效降低患者血糖,提高HDL-C水平,值得在临床上广泛推广和应用。
Objective To observe the effect of pitavastatin on diabetic hypercholesterolemia. Methods 100 cases of hypercholesterolemia patients with diabetes were randomly divided into control group and observation group, 50 cases in each group. Two groups of patients were given conventional hypoglycemic therapy, on this basis, the control group was treated with atorvastatin, the observation group was treated with pitavastatin. The fasting blood glucose, high density lipoprotein cholesterol (HDL-C) and the incidence of adverse reactions in both groups were observed. Results The incidence of fasting blood glucose, HDL-C and adverse reactions in observation group were significantly higher than those in control group, with statistical significance (P <0.05). Conclusion Pitavastatin treatment of diabetic hypercholesterolemia effect is significant, can effectively reduce blood glucose and increase HDL-C levels, it is widely used in clinical practice.