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目的:探讨不同妊娠期细菌性阴道病(BV)发病、自然转归及对胎膜早破、早产的影响。方法:对662例孕妇在妊娠早、中、晚期进行BV检查,跟踪随访至分娩,分析不同妊娠期BV发病、缓解、病程对胎膜早破、早产的影响。结果:662例妊娠期妇女中检出BV患者98例(14.80%),妊娠期BV患者胎膜早破、早产发病率明显高于正常妊娠妇女(P<0.01),妊娠中、晚期BV发病率明显高于妊娠早期(P<0.01),妊娠早期BV自然缓解率明显高于妊娠中期(P<0.05)。随着妊娠期BV病程延长胎膜早破、早产发生率增加。结论:妊娠中、晚期妇女应进行BV筛查,妊娠期BV患者应及时治疗、跟踪随访以减少胎膜早破、早产等不良妊娠结局的发生。
Objective: To investigate the different incidence of bacterial vaginosis (BV) during pregnancy, natural outcome and the impact of premature rupture of membranes and premature rupture of membranes. Methods: 662 pregnant women in the early, middle and late pregnancy BV examination, follow-up to childbirth, analysis of different stages of pregnancy BV onset, remission, duration of premature rupture of membranes, the impact of preterm birth. Results: 98 cases (14.80%) of BV patients were detected in 662 pregnant women. The incidence of premature rupture of membranes and premature birth in BV patients during pregnancy were significantly higher than those in normal pregnant women (P <0.01). The incidence of BV in middle and late pregnancy Significantly higher than that of early pregnancy (P <0.01). The natural remission rate of BV in early pregnancy was significantly higher than that of mid-pregnancy (P <0.05). With the extension of pregnancy during BV prolonged premature rupture of membranes, the incidence of preterm birth increased. Conclusion: BV should be screened in middle and late pregnancy. Patients with BV in pregnancy should be treated promptly and follow-up should be followed up to reduce the occurrence of adverse pregnancy outcomes such as premature rupture of membranes and premature labor.