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为评价精华口服液的保肝作用，取雄性SD大鼠，每周2次，连续3个月口服用植物油配制的25％CCl4溶液，造成慢性肝损伤．然后分别服用精华口服液（实验组）和云芝肝素（阳性对照组）。对体重增长、存活率、AST、ALT、唾液酸、肝胶元含量、肝脏重／体重的观测及病理学检查结果表明，对由四氯化碳引起的大鼠慢性肝损伤，精华口服液具有与云芝肝泰相似的治疗作用．且精华口服液大、小剂量之间的药效作用呈剂量依赖性。
To evaluate the hepatoprotective effect of Essence Oral Liquid, male Sprague-Dawley rats were used twice a week for three consecutive months to take 25% CCl4 solution of vegetable oil, resulting in chronic liver injury. Then take the best oral solution (experimental group) and Yunzhi heparin (positive control group). Observations on body weight gain, survival rate, AST, ALT, sialic acid, hepatic collagen content, liver weight / body weight and pathological examination showed that for the chronic liver injury caused by carbon tetrachloride in rats, And Yunzhi Gan Thai similar therapeutic effect. And the essence of oral liquid large, small dose of the drug effect in a dose-dependent manner.