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目的应用常用筛查方法鉴别诊断153例孕期妇女的轻型β-地中海贫血和缺铁性贫血并进行结果分析。方法轻型β-地贫组、缺铁性贫血组,检测红细胞6项参数及血清铁(SI)、血清铁蛋白(SF)。结果红细胞6项参数,RBC:IDA组显著降低,轻型β-地贫组显著升高;Hb:IDA组及轻型β-地贫组显著降低;MCV和MCH:IDA组及轻型β-地贫组显著降低;MCHC:IDA组显著降低;RDW:IDA组显著升高。IDA组SI、SF均显著降低;轻型β-地贫组SF显著增高。结论红细胞6项参数和SF对轻型β-地贫与缺铁性贫血有鉴诊断意义。
Objective To identify and diagnose mild β-thalassemia and iron-deficiency anemia in 153 pregnant women by common screening methods. Methods Sixty-three parameters of erythrocyte, serum iron (SI) and serum ferritin (SF) were detected in patients with mild β-thalassemia and iron deficiency anemia. Results 6 parameters of erythrocytes were significantly decreased in RBC: IDA group and significantly in light β-thalassemia group; Hb: IDA group and light β-thalassemia group were significantly decreased; MCV and MCH: IDA group and light β-thalassemia group Significantly decreased; MCHC: IDA group significantly reduced; RDW: IDA group significantly increased. The SI and SF in IDA group were significantly lower than those in the mild β-thalassemia group. Conclusion 6 parameters of erythrocytes and SF have clinical significance in diagnosing light β-thalassemia and iron deficiency anemia.