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AIM:To investigate the effects of c type natriuretic peptide (CNP) on cerebral infarction.METHODS:Plasma levels of CNP were concomitantly measured by radioimmunoassay in 30 patients with cerebral infarction and in 30 normal controls.RESULTS:Plasma levels of CNP were increased significantly in the acute stage of cerebral infarction than those in the normal controls(P< 0.01) and levels in the moderate and serious cases were lower than those in the slight cases(P< 0.01).CONCLUSION:In cerebral infarction the increase of plasma CNP was in accordance with the severity of the disease .CNP in the pathophysiology of acute cerebral ischemia had a deleterious effect on the evolution of cerebral infarction.
AIM: To investigate the effects of c type natriuretic peptide (CNP) on cerebral infarction. METHODS: Plasma levels of CNP were concomitantly measured by radioimmunoassay in 30 patients with cerebral infarction and in 30 normal controls .RESULTS: Plasma levels of CNP were significantly increased in the acute stage of cerebral infarction than those in the normal controls (P <0.01) and levels in the moderate and serious cases were lower than those in the slight cases (P <0.01) .CONCLUSION: In cerebral infarction the increase of plasma CNP was in accordance with the severity of the disease. CNP in the pathophysiology of acute cerebral ischemia had a deleterious effect on the evolution of cerebral infarction.