本文取家兔43只,其中40只分别接种感染日本血吸虫尾蚴200±5条;另3只做正常对照。感染兔分为四组处理,即:热疗加复方五味子组;热疗加百合桂枝组;单热疗组;对照组。以上四组均于接种后14周用吡喹酮100mg/kg顿服杀虫,并于16周后以剖腹直观并切取肝组织块进行观察。发现复方五味子组与百合桂枝组能使肝胶原纤维明显降解,而单纯热疗组和对照组效果不明显,并就其机理作了初步探讨。 In this study, 43 rabbits were used, 40 of which were inoculated with 200±5 cercariae of Schistosoma japonicum. The other 3 were used as normal controls. Infected rabbits were divided into four groups, namely: hyperthermia plus compound schisandra group; hyperthermia plus liliguizhi group; single hyperthermia group; control group. All the above four groups were sterilized with praziquantel 100 mg/kg at 14 weeks after inoculation, and were observed after laparotomy at 16 weeks and hepatic tissue was removed. It was found that compound Schisandra chinensis and Lilium Glutinosa group can significantly degrade liver collagen fibers, but the effects of hyperthermia and control groups were not obvious, and the mechanism was initially discussed.