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Objective: To study the relationship between blood stasis syndrome (BSS) and platelet activation and its influencing factors in type 2 diabetic mellitus (DM).Methods: Platelet CD 62p , CD 63 expressions were determined in 30 type 2 DM patients with BSS, 27 type 2 DM patients without BSS and 20 normal controls by flow cytometry. Results: CD 62p , CD 63 levels were significantly higher in type 2 DM group with BSS than those in the type 2 DM group without BSS and in the normal controls. CD 62p was positively correlated with CD 63 , while positive correlation existed between HbA 1c, LDLC and CD 62p in DM patients with BSS. Conclusions: The increased level of platelet activation was the primary molecular basis of BSS in type 2 DM. It was important to perform the syndrome differentiation of BSS and treatment of activating blood flow to remove BSS in type 2 DM.
Objective: To study the relationship between blood stasis syndrome (BSS) and platelet activation and its influencing factors in type 2 diabetic mellitus (DM). Methods: Platelet CD 62p, CD 63 expressions were determined in 30 type 2 DM patients with BSS, 27 type 2 DM patients without BSS and 20 normal controls by flow cytometry. Results: CD 62p, CD 63 levels were significantly higher in type 2 DM group with BSS than those in type 2 DM group without BSS and in the normal controls. CD 62p was positively correlated with CD 63, while positive correlation existed between HbA 1c, LDLC and CD 62p in DM patients with BSS. Conclusions: The increased level of platelet activation was the primary molecular basis of BSS in type 2 DM. It was important to perform the syndrome differentiation of BSS and treatment of activating blood flow to remove BSS in type 2 DM.