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目的分析乌鲁木齐市第四人民医院分院门诊部药品不良反应发生的特征及规律,为合理用药提供警示。方法对2009年3月—2011年上6月86例药物不良反应报告进行分析。结果 86例不良反应中涉及药物15种,以抗生素类所致的不良反应居多,其中以头孢菌素类占首位,占54%;其次为中药制剂,占14%;静脉注射是引起不良反应的主要给药途径;不良反应累及的系统以皮肤系统损害为主,占47.67%。结论临床工作中应重视药物不良反应,强调合理安全用药,避免不良反应发生率,保证患者用药安全。
Objective To analyze the characteristics and regularities of adverse drug reactions in outpatient department of the Fourth People ’s Hospital of Urumqi to provide warnings for rational drug use. Methods 86 cases of ADR reported from March 2009 to June 2011 were analyzed. Results A total of 86 adverse reactions were involved in 15 kinds of drugs, with the majority of adverse reactions caused by antibiotics, of which cephalosporins accounted for 54%, followed by traditional Chinese medicine preparations, accounting for 14%. Intravenous injection was the cause of adverse reactions The main route of administration; adverse reactions involving the system of skin damage, accounting for 47.67%. Conclusion Clinical work should pay attention to adverse drug reactions, emphasizing the rational use of safe drugs to avoid the incidence of adverse reactions to ensure the safety of patients medication.