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目的观察联合辛伐他汀和银杏达莫治疗急性脑梗死的疗效。方法将36例脑梗死患者随机分为三组,辛伐他汀组(常规治疗加用辛伐他汀)、联合组(常规治疗加用辛伐他汀联合银杏达莫)、对照组(常规治疗)各12例。观察临床疗效、NIHSS评分、Barthel指数评分。结果各组治疗前NIHSS评分和Barthel指数评分均无显著差异(P>0.05),辛伐他汀组和联合组临床治愈率显著高于对照组,而NIHSS评分及Barthel指数评分显著低于对照组(P<0.05),其中联合组治疗效果优于辛伐他汀组(P<0.05)。结论辛伐他汀联合银杏达莫治疗急性脑梗死可发挥协同作用。
Objective To observe the curative effect of combined simvastatin and gingko-damo on acute cerebral infarction. Methods Thirty-six patients with cerebral infarction were randomly divided into three groups: simvastatin group (routine therapy plus simvastatin), combination group (conventional therapy plus simvastatin plus ginkgo biloba), and control group 12 cases. Clinical efficacy, NIHSS score and Barthel index score were observed. Results The scores of NIHSS and Barthel index were not significantly different before treatment in each group (P> 0.05). The clinical cure rates in simvastatin group and combination group were significantly higher than those in control group, while NIHSS score and Barthel index score were significantly lower than those in control group P <0.05). The combined treatment group was superior to simvastatin group (P <0.05). Conclusion Simvastatin combined with ginkgo biloba can play a synergistic effect in the treatment of acute cerebral infarction.