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Objective:To study the clinical characteristics,the optimal treatments and the prognosis of the recurrent and persistent malignant ovarian germ cell tumors(MOGCT). Methods:The clinical data of 17 recurrent and persistent MOGCT cases treated in Peking Union Medical College Hospital from January 1983 to May 2008 were analyzed retrospectively.The primary and the secondary treatment were analyzed. Results;Only 4 cases of recurrent MOGCT undergone comprehensive surgical staging at primary operation. Sixteen cases received non-standardized chemotherapy.After 1 to 8 months,the recurrent tumors were found.The secondary debulking surgery was done in fifteen patients.The standardized chemotherapy was used postoperatively. After that,eight patients were still tumor-free and alive.Five patients deceased including four patients who gave up treatment.Four patients were lost to follow up. Conclusion:The standardized treatment should be emphasized for the MOGCT.Even for the recurrent and persistent MOGCT,the satisfied cytoreductive surgery plus the adjuvant standardized chemotherapy also show the significant impact on the prognosis of the recurrent and persistent MOGCT patients.
Objective: To study the clinical characteristics, the optimal treatments and the prognosis of the recurrent and persistent malignant ovarian germ cell tumors (MOGCT). Methods: The clinical data of 17 recurrent and persistent MOGCT cases treated in Peking Union Medical College Hospital from January 1983 to May 2008 were analyzed retrospectively. The primary and the secondary treatment were analyzed. Results; Only 4 cases of recurrent MOGCT undergone comprehensive surgical staging at primary operation. Sixteen cases received non-standing chemotherapy. After 1 to 8 months, the recurrent tumors were found.The secondary debulking surgery was done in fifteen patients.The standardized chemotherapy was used postoperatively. After that, eight patients were still tumor-free and alive.Five patients deceased including four patients who gave up treatment.Four patients were lost to follow up Conclusion: The standardized treatment should be emphasized for the MOGCT. Even for the recurrent and persistent MO GCT, the satisfied cytoreductive surgery plus the adjuvant programmable also show the significant impact on the prognosis of the recurrent and persistent MOGCT patients.