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目的:讨论内镜下黏膜剥离术(ESD)治疗消化道早期肿瘤及癌前病变的临床疗效。方法:回顾性分析本院2014年3月至2015年12月收治的26例行ESD的消化道早期肿瘤及癌前病变患者作为观察组,选取同时行普通外科手术治疗的26例消化道早期肿瘤及癌前病变患者作为对照组。对比两组患者的病灶切除情况、手术时间、住院时间、治疗费用以及并发症发生率。结果:两组患者的治愈性切除率、术后生存率以及术后复发率对比,差异均无统计学意义(P>0.05);观察组患者的手术时间、住院时间、治疗费用以及并发症发生率均显著优于对照组患者,差异具有统计学意义(P<0.05)。结论:针对消化道早期肿瘤及癌前病变患者,采用ESD与常规外科手术的治疗效果相当,但ESD具有创伤小、手术时间短、住院时间短、治疗费用低以及并发症发生率低等优势。
Objective: To discuss the clinical efficacy of endoscopic mucosal dissection (ESD) in the treatment of early gastrointestinal cancer and precancerous lesions. Methods: A retrospective analysis of our hospital from March 2014 to December 2015 admitted to the 26 patients with ESD digestive tract precancerous lesions and patients as the observation group, selected at the same time underwent common surgical treatment of 26 cases of early digestive tract tumors And precancerous lesions as a control group. The resection, operation time, hospitalization time, treatment cost and complication rate of the two groups were compared. Results: There was no significant difference in curative resection rate, postoperative survival rate and postoperative recurrence between the two groups (P> 0.05). The operation time, hospitalization time, treatment cost and complications Rate were significantly better than the control group, the difference was statistically significant (P <0.05). Conclusion: For the patients with early digestive tract tumors and precancerous lesions, the treatment effect of ESD is similar to that of conventional surgery. However, ESD has the advantages of small trauma, short operation time, short hospital stay, low cost of treatment and low complication rate.