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目前临床用于治疗冠心病心绞痛的药物主要有硝酸酯类、β阻滞剂和钙通道阻滞剂三大类,各有其特点,但都是以改善心肌血流的供求平衡为目标。近年来,对这几类药物的作用机制、适应症、副作用以及合理选用等方面,都有新的认识。但也存在一些争议,有些严重不良反应并未引起足够重视。本文就抗心绞痛药物在冠心病治疗中应注意的几个问题作一简述。
Currently clinically used for the treatment of coronary heart disease angina mainly nitrate drugs, beta blockers and calcium channel blockers three categories, each with its own characteristics, but are to improve the balance between supply and demand of myocardial blood flow as the goal. In recent years, there are new understandings on the mechanism, indications, side effects and rational selection of these types of drugs. But there are also some controversy, some serious adverse reactions did not pay enough attention. This article gives a brief account of several issues that anti-angina drugs should pay attention to in the treatment of coronary heart disease.