目的:探讨分析妊娠合并甲状腺功能减退患者并发症情况,对孕妇妊娠结局的影响,总结有效的治疗方法。方法:将我院收治的184例妊娠合并甲状腺功能减退患者按照是否采取相应的治疗措施分为治疗组和未治疗组,并选取同期在我院进行孕检的正常孕妇80例作为对照,对比分析三组孕妇的临床资料。结果:合并症及并发症情况:治疗组、未治疗组以及对照组孕妇妊娠合并胎膜早破的发生率并无明显差异(P>0.05),未治疗组患者合并妊娠期糖尿病、妊娠高血压、胎位异常的发生率明显高于对照组(P<0.05),治疗组患者合并妊娠高血压的发生率明显低于未治疗组(P<0.05);治疗组患者与对照组相比,合并症发生情况并无明显差异(P>0.05)。妊娠结局:未治疗组患者剖宫产率、胎儿畸形、新生儿窒息、早产、新生儿甲状腺功能减退等发生率明显高于对照组(P<0.05);治疗组与对照组的妊娠结局并无明显差异(P>0.05)。结论:妊娠期合并甲状腺功能减退会影响孕妇妊娠结局,应加强妊娠前期及早期妇女,尤其是具有甲状腺疾病高危风险妇女的甲状腺功能筛查,左旋甲状腺治疗妊娠合并甲状腺功能减退的临床疗效显著,可有效减少不良妊娠结局发生率。 Objective: To investigate the analysis of complications in patients with hypothyroidism in pregnancy, pregnancy outcomes of pregnant women, summarize the effective treatment. Methods: A total of 184 pregnant women with hypothyroidism admitted to our hospital were divided into treatment group and untreated group according to whether the corresponding treatment measures were taken or not, and 80 normal pregnant women who were pregnant in our hospital during the same period were selected as control. Three groups of pregnant women’s clinical data. Results: Complications and complications: There was no significant difference in the incidence of premature rupture of membranes between treatment group, untreated group and control group (P> 0.05). Patients in untreated group had gestational diabetes mellitus, pregnancy-induced hypertension , The incidence of abnormal fetal position was significantly higher than that of the control group (P <0.05), and the incidence of pregnancy-induced hypertension in the treatment group was significantly lower than that of the untreated group (P <0.05). Comparing the treatment group with the control group, There was no significant difference (P> 0.05). Pregnancy outcome: The incidence of cesarean section rate, fetal malformation, neonatal asphyxia, premature birth, neonatal hypothyroidism in untreated group was significantly higher than that in control group (P <0.05). Pregnancy outcome in treatment group and control group was not Significant difference (P> 0.05). Conclusions: Hypothyroidism during pregnancy may affect the pregnant outcome of pregnant women. Thyroid function screening should be strengthened in pre-pregnancy and early-stage women, especially in women at high risk of thyroid disease. The clinical efficacy of L-thyroid treatment for pregnancy complicated with hypothyroidism is significant. Effectively reduce the incidence of adverse pregnancy outcomes.