用离子交换树脂法对河豚鱼卵巢的有效成分进行提取。这种提取物不含蛋白质和氨基酸 ,硅胶 GF2 54 板层析 ,三种展开剂展层 ,只呈现一个斑点 ,ICP- AES法测定表明 ,含有与人体基本相同的 15种微量元素和 5种常量元素 ,富含 Ca,Fe,Zn等。热稳定性好 ,室温放置 4个月仍保持稳定的生物活性。并且具有凝集动物红细胞、小鼠脾细胞、胸腺细胞和小鼠 S180 肉瘤细胞的生物活性 ,经化学显色测定提取物可能属于动物生物碱类。 The ion exchange resin method was used to extract the active ingredients of puffer fish ovary. This extract contains no protein or amino acids. The silica gel GF2 54 plate chromatography showed only one speck of the three developing agents. ICP-AES showed that there were 15 kinds of trace elements and 5 kinds of constants Elements, rich in Ca, Fe, Zn and so on. Good thermal stability, at room temperature for 4 months still maintain a stable biological activity. And has the biological activity of aggregating animal erythrocytes, mouse spleen cells, thymocytes and mouse S180 sarcoma cells, and the extracts may be classified as animal alkaloids by chemical colorimetry.