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沙眼衣原体(chlamydia trachomatis,CT)是引起性传播疾病的主要病原体之一,能感染并裂解衣原体的一类细菌病毒称为衣原体噬菌体。从不同种类的衣原体中分离出的噬菌体共有6种:Chp1,Chp2,Chp3,Chp4,CPAR39和PhiCPG1。虽然至今未能从沙眼衣原体中成功分离出噬菌体,但关于噬菌体衣壳蛋白Vp1,Vp2及Vp3的研究提示沙眼衣原体噬菌体存在的可能性。有关沙眼衣原体噬菌体的研究可为沙眼衣原体感染的诊断和治疗提供重要的临床思路和方法。
Chlamydia trachomatis (CT) is one of the major pathogens responsible for sexually transmitted diseases. A group of bacterial viruses that can infect and lyse Chlamydia are called chlamydial phages. There are 6 kinds of bacteriophages isolated from different kinds of Chlamydia: Chp1, Chp2, Chp3, Chp4, CPAR39 and PhiCPG1. Although bacteriophages have so far not been successfully isolated from C. trachomatis, studies on the phage capsid proteins Vp1, Vp2 and Vp3 suggest the possibility of the presence of phages of C. trachomatis. Research on Chlamydia trachomatis bacteriophage can provide important clinical ideas and methods for the diagnosis and treatment of Chlamydia trachomatis infection.