目的了解2005~2013年丹东市疟疾病例的流行特点,为制定疟疾防控策略和实现消除疟疾计划提供科学依据。方法利用中国疾病预防控制信息系统和丹东市疾病预防控制中心多年来收集的疟疾病例信息,对丹东市2005~2013年疟疾病例的发病和流行特征进行分析。结果 2005~2013年,丹东市共报告疟疾病例52例,疟疾发病在地区分布(χ2=33.77,P<0.01)、性别(χ2=24.38,P<0.01)、职业别(χ2=20.20,P<0.01)、发病月份(χ2=32.89,P<0.01)和各年份感染类型(χ2=38.63,P<0.01)间差异有统计学意义。疟疾本地病例以间日疟为主,呈逐年减少趋势,输入病例以恶性疟为主,呈逐年增多趋势,且88.46%的输入病例与非洲劳务输出有关。有40.38%的病例在病后1~3d内就诊,所有病例病后平均就诊时间为13.84d,其中初次发病平均病后就诊时间为9.6d,复发病例平均病后就诊时间为18.27d;69.23%的病例由县(市)级医院报告;经多年开展监测点居民入户调查,居民防蚊意识和疟疾知晓率均有所提高。结论文化程度较低的男性中老年出国劳务民工是丹东市输入性疟疾的主要人群,基层医疗机构疟疾诊断水平亟待提高;今后要继续开展以医院为基础的疟疾监测并适时开展以社区为基础的监测和现场调查工作。 Objective To understand the epidemiological characteristics of malaria cases in Dandong City from 2005 to 2013 and to provide a scientific basis for malaria prevention and control strategies and malaria elimination programs. Methods Using the information of malaria cases collected by China Disease Prevention and Control Information System and Dandong Municipal Center for Disease Control and Prevention over the years, the incidence and epidemic characteristics of malaria cases in Dandong from 2005 to 2013 were analyzed. Results From 2005 to 2013, 52 cases of malaria were reported in Dandong City. The incidence of malaria was distributed in different regions (χ2 = 33.77, P <0.01), sex (χ2 = 24.38, 0.01). There was significant difference between the onset month (χ2 = 32.89, P <0.01) and infection type in each year (χ2 = 38.63, P <0.01). The local cases of malaria were predominately vivax malaria, showing a declining trend year by year. The imported cases were dominated by falciparum malaria and showed an increasing trend year by year. And 88.46% of the imported cases were related to the export of labor services in Africa. 40.38% of the cases were treated within 1 ~ 3 days after the illness. The mean duration of illness after all the cases was 13.84 days, of which the average time to first visit was 9.6 days, the mean time to relapse after the illness was 18.27 days, 69.23% Of cases reported by the county (city) level hospitals; after years of monitoring households to carry out household survey, residents awareness of mosquitoes and awareness of malaria have increased. Conclusions The low-educated male middle-aged and elderly migrant laborers are the main population of imported malaria in Dandong City. The level of malaria diagnosis needs to be improved in primary medical institutions. In the future, hospital-based malaria surveillance should be continued and community-based Monitoring and site investigation.