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目的了解艾滋病病毒(HIV)感染者/艾滋病(AIDS)病人(HIV/AIDS病人)中,甲型H1N1流行性感冒(流感)感染状况,分析研究HIV/AIDS病人的CD+4T淋巴细胞(简称CD4细胞)水平,对甲型H1N1流感病毒抗体水平的影响,为评价甲型H1N1流感、HIV/AIDS病人现有防控策略和措施提供技术支持。方法对252例HIV/AIDS病人进行问卷调查,并采集静脉血2~5mL检测流感抗体。对问卷调查结果及实验室检测结果以Excel为基础建立数据库,应用SPSS 17.0软件对资料进行分析。结果 252例HIV/AIDS病人中,甲型H1N1流感抗体阳性40例,阳性率15.9%,阴性212例(84.1%)。流感抗体阳性与阴性者比较显示,CD4细胞水平、有无接种甲型流感疫苗的差异有统计学意义,年龄、性别、婚姻状况、教育程度等情况差异无统计学意义。HIV/AIDS病人与健康人群甲型H1NI流感的抗体阳性率差异有统计学意义。结论 HIV/AIDS病人因免疫力低下可优先考虑接种流感疫苗。低CD4细胞水平是感染甲型H1N1流感的危险因素。
Objective To investigate the prevalence of Influenza A (H1N1) influenza among HIV / AIDS patients (HIV / AIDS patients) and to analyze the prevalence of CD + 4T lymphocytes (CD4 Cells) levels on the antibody level of Influenza A (H1N1) virus and provide technical support for the evaluation of the existing prevention and control strategies and measures for Influenza A (H1N1) and HIV / AIDS patients. Methods A total of 252 HIV / AIDS patients were surveyed and 2 to 5 mL venous blood samples were collected for the detection of influenza antibodies. The questionnaire survey results and laboratory test results to Excel based database, application SPSS 17.0 software for data analysis. Results Among 252 HIV / AIDS patients, 40 were positive for Influenza A (H1N1) antibody, with a positive rate of 15.9% and a negative rate of 212 (84.1%). Influenza antibody positive and negative comparison, CD4 cell levels, with or without influenza A vaccination were statistically significant, age, gender, marital status, educational level and other differences were not statistically significant. The antibody positive rate of Influenza A (H1NI) in HIV / AIDS patients and healthy people was significantly different. Conclusion HIV / AIDS patients may give priority to influenza vaccination because of their low immunity. Low CD4 cell levels are a risk factor for Influenza A (H1N1) infection.